Frontline Plus Flea and Tick Treatment for Small Dogs, 5–22 lb, 6 Doses

FRONTLINE Plus is a monthly topical flea and tick treatment for small dogs weighing 5–22 lb (2.3–10 kg), supplied as a six-dose pack.

• One dose protects for 30 days — a monthly application provides ongoing flea and tick control.
• Fipronil and (S)-methoprene kill adult fleas, flea eggs and flea larvae — targeting multiple stages of the flea life cycle.
• Also kills chewing lice and ticks that can transmit Lyme disease — covering several common external parasites.
• Waterproof formula works even if your dog gets wet — treatment is distributed through the skin’s sebaceous glands.
• For puppies from eight weeks old and dogs weighing at least 5 lb (2.3 kg) — a defined age and weight range helps guide selection.

Fleas can continue their life cycle beyond the adult insects on a dog, so this treatment is formulated to address adult fleas as well as eggs and larvae. FRONTLINE Plus is made for monthly flea and tick control on dogs, including small-breed dogs in its stated weight range. FRONTLINE was identified as the number 1 name in flea and tick protection in a BI Marketing Excellence Survey conducted by Kynetec in November 2023; the brand also reports more than 20 years of pet-owner trust in its flea and tick products.

What parasites does FRONTLINE Plus for small dogs kill?

It kills adult fleas, flea eggs, flea larvae, chewing lice and ticks that can transmit Lyme disease. Its two active ingredients are fipronil and (S)-methoprene: fipronil targets existing adult fleas and ticks, while the combination also targets flea eggs and larvae to help interrupt the flea life cycle.

• Targets existing adult fleas as well as immature flea stages.
• Designed to help guard against further flea infestations.

How does the monthly topical treatment work?

Apply the treatment to a single point on your dog; it then covers the body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your dog. The waterproof formula continues working if your dog gets wet, and one dose provides flea and tick protection for a full 30 days.

• Fast-acting, long-lasting topical treatment.
• One application point; the treatment spreads over the dog’s body.

Which dogs is this six-dose pack for?

This pack is intended for dogs weighing 5–22 lb (2.3–10 kg). FRONTLINE Plus can be used on puppies from eight weeks of age when they weigh at least 5 lb (2.3 kg), so both age and weight matter when choosing this dog formula.

• Pack quantity: six monthly doses.
• Orange identifies this small-dog product variant.

For household flea control, the brand advises treating all dogs and cats monthly to help control fleas and prevent new infestations from becoming established. FRONTLINE also offers a separate formula for cats and kittens from eight weeks old and weighing at least 1.5 lb; this six-dose product is the small-dog formula, not the cat formula. It best suits owners seeking monthly topical flea and tick protection for a dog within the stated weight range, with treatment that targets adult fleas and earlier flea stages and keeps working if the dog gets wet.

Ingredients

Active Ingredient: fipronil 9.8%, (S)-methoprene) 8.8%Inert Ingredients: 81.4%